LGD-3303: A Very Promising SARM That Is Still In Its Development Stage

LGD-3303 is a selective androgen receptor modulator (SARM) that comes with impeccable oral bioavailability. The drug is categorized as a selective agonist designed for the androgen receptor. LGD-3303 has both anabolic and androgenic effects and at the moment the drug is being researched as a possible solution to treat osteoporosis.

This is a condition that leads to increased bone weakness in humans.  LGD-3303 is one of the most potent SARMs out there and for many bodybuilders who want to bulk muscle, LGD-3303 stacked with other equally effective SARMs can offer the ultimate combination.


LGD-3303 is currently being developed and researched by Lingad Pharmaceuticals. The chemical structure of the drug closely reassembles that of LGD-4033 which is also another SARM that has since been developed by the same company. However, LGD-3303 is still not available on the market the same way LGD-4033 is.

Trials that have been done so far on LGD-3303 show that it has the potential to significantly increase muscle mass and prevent muscle wasting. Although it can be argued that other SARMs can achieve the same thing, it is clear that LGD-3303 is a little bit more effective albeit it’s still in the development phase.

LGD-3303 is a non-steroidal orally active SARM and while its effect in helping with muscle mass and increased androgenic action is huge, its effect on androgenic organs in the body in the tests subjects was very small.

How it Works

LGD-3303 has been developed to help address a wide range of conditions. However, the most important is its ability to maintain the beneficial effects of androgens in improving muscle mass and bone density without side effects. Although the selective mechanism of LGD-3303 and other SARMs is not yet clearly understood even with ongoing research, it is clearly a big leap from the usual anabolic steroids. Once LGD-3303 is injected into the body or taken orally, it will trigger androgenic action on a cellular level.

diagram of the molecular structure for LGD-3303

However, it should be remembered that the human body contains millions of cells and a substance that triggers androgenic effects in each of these cells would have devastating side effects. That is why LGD-3303 is termed as selective. Instead of triggering androgenic action in all cells, it will only target muscle tissue and skeletal cells.

This is the main reason why LGD-3303 has been used as a supplement in bodybuilding and also as a possible treatment for people who have issues with bone density. LGD-3303 could also have other positive benefits. However, because the drug is still under research, these potential benefits are not yet clear.

How it is Administered

In the test subjects that have been used to assess the potency of LGD3303 as a SARM, the drug has been administered in two ways. To start with, LGD-3303 can be injected into the bloodstream.  It can also be taken orally. However, it is recommended that for humans the SARM should be taken orally. LGD-3303 comes in liquid capsules and can be taken using water or juice. The problem with using an injection is that it becomes very hard to maintain the dosage.

Advantages of Using This SARM

  • Although LGD-3303 is still an experimental SARM, there are a few potential benefits that it could offer. To start with, LGD-3303 is able to offer effective androgenic action without affecting androgenic organs. This is a big plus because compared to steroids which were earlier used as substitutes for SARMs, the side effects are very minimal.
  • LGD-3303 has the potential to aid in increased muscle mass and bone density. For bodybuilders, this is a very important feature. While to be fair most SARMs will influence building up muscle, on the tests done so far, LGD-3303 has been very effective.
  • LGD-3303 has also been seen to have an effect in improving the metabolic action. This is significant in the sense that people who want to cut fat can leverage on the SARM as an aid to achieve their fat loss goals. However, stacking LGD-3303 with other equally effective SARMs and having a strong exercise regimen is important if results will be achieved.

Disadvantages of Using

LGD-3303 is still in the trial phase and therefore it’s not easy to say whether there are any side effects or not. However, so far the review of the drug and its effect on mice have shown it has very little effect on androgenic organs.

Side Effects

As LGD-3303 is a trial drug, there is very little information regarding its potential side effects. But the information we have so far suggest that it is perfectly safe to use with very negligible side effects on androgenic organs.

Dosage to Be Taken

  • Cutting – The dosage for LGD-3303 is still being fine-tuned as research on the drug continues. However, for great effects on cutting, a dosage of between 15 mg and 20 mg for a cycle of 6 to 8 weeks is recommended.
  • Bulking – LGD-3303 has amazing effects on building muscle mass and in order to get results, you’ll need a dosage of between 20 mg to 30 mg per day for a cycle of 8-10 weeks.
  • Recomping – The same dosage for bulking will also work for recomping. 20 mg to 30 mg for a cycle of 8-10 weeks will do. However, as research on LGD-3303 continues, dosage information might also change.

Is PCT needed?

So far, research studies have shown that even as LGD-3303 delivers impeccable androgenic effects, it does not affect androgenic organs in the body. This means that it will not affect the natural production of testosterone and therefore PCT will not be needed.

Can Women Use It?

Yes, women can use LGD-3303. Remember this is not a hormone and it’s also a non-steroidal drug with no effects on androgenic organs. The risk of virilization is therefore zero.

Other SARMs That Stack Well

You can stack LGD-3303 with the following SARMs:

  • GW-501516
  • LGD-4033

What is the Half-Life?

The half-life of LGD-3303 is at the moment 12 hours. This means that you’ll have to use the dosage noted above twice a day for the best results.

How Long Until You See Results

It will take just a few weeks to see results but it’s best to be patient until the full cycle is done. That is when the full impact of LGD-3303 will be visible.

Will it make an Athlete Fail a Drug Test?

Yes, it is possible to fail a drug test using LGD-3303. However, because the SARM is still new, the World Anti-Doping Agency is yet to develop a test for it.

How to Buy

You can only buy LGD-3303 online at the present time. The drug is not yet in full distribution so getting it in your local store will be quite difficult.

What Are the Current Laws?

LGD-3303 is not an illegal substance and therefore using it will not be interpreted as breaking the law in the US.

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